Supporting People With ALL From the First Dose Forward

An acute lymphoblastic leukemia patient sits and talks with their friend over coffee.
An acute lymphoblastic leukemia patient talks on their cellphone.

Learn about Servier patient support

A diagnosis of acute lymphoblastic leukemia (ALL) can be overwhelming. That’s why Servier offers a range of support services, including free product to those who qualify, compassionate guidance, and helpful tools and resources.

FAQs

ALL is a cancer of the blood and bone marrow characterized by the rapid growth and spread of immature white blood cells (WBCs), which are also known as lymphoblasts or leukemic cells.


Here’s what happens in ALL: Too many immature WBCs are made in the bone marrow. The immature WBCs do not develop into healthy cells and cannot fight infections. They grow faster, live longer than normal cells, and make multiple copies of themselves, crowding out healthy cells that the body needs.


If untreated, all of those immature cells spill out into the bloodstream and begin to cause problems elsewhere in the body, such as in the spleen, thymus, lymph nodes, liver, testicles, and central nervous system.

Learn more about personalized support

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Three acute lymphoblastic leukemia patients pose together and smile.

IMPORTANT SAFETY INFORMATION

IMPORTANT SAFETY INFORMATION Section

ONCASPAR should not be given to patients who have had:

  • Serious allergic reactions to ONCASPAR (pegaspargase) or any of its ingredients
  • Serious blood clots, serious swelling of the pancreas (abdominal pain), or serious bleeding during previous L-asparaginase treatment
  • Serious impairment of liver function

IMPORTANT SAFETY INFORMATION

ONCASPAR should not be given to patients who have had:

  • Serious allergic reactions to ONCASPAR (pegaspargase) or any of its ingredients
  • Serious blood clots, serious swelling of the pancreas (abdominal pain), or serious bleeding during previous L-asparaginase treatment
  • Serious impairment of liver function

ONCASPAR may cause serious side effects including:

  • Allergic reactions (Symptoms: hives and itching, a swollen tongue or throat, trouble breathing, dizziness, fainting)
  • Swelling of the pancreas (Symptoms: severe stomach pain, nausea, vomiting, fever, chills, diarrhea)
  • Blood clots (Symptoms: severe headache, arm or leg swelling, shortness of breath, chest pain)
  • Increased/excess sugar in the blood (Symptoms: Excessive thirst, increased amount of urine or urinary frequency)
  • Unusual bleeding or bruising
  • Abnormal liver function or damage (Symptoms: jaundice, severe nausea, vomiting)

Call or see your doctor right away if you develop any of these serious side effects or if symptoms get worse.

Before receiving ONCASPAR, tell your doctor about all your medical conditions, including if you:

  • are pregnant or plan to become pregnant. ONCASPAR can harm your unborn baby. You should not become pregnant during treatment with ONCASPAR. Tell your doctor right away if you become pregnant or think you may be pregnant during treatment with ONCASPAR.
  • Females who are able to become pregnant: You should use effective non-hormonal birth control (contraception) during treatment with ONCASPAR and for at least 3 months after the last dose.
  • are breastfeeding or plan to breastfeed. It is not known if ONCASPAR passes into your breast milk. Do not breastfeed during treatment with ONCASPAR and for 1 month after your last dose.

How will I receive ONCASPAR?

  • ONCASPAR will be given to you as an injection by your doctor as part of your chemotherapy treatment plan. It is important that you receive all of your treatment doses according to your doctor’s instructions.
  • During treatment, you will be monitored, and if you experience side effects, your doctor may have to change your treatment.

The most common side effects of ONCASPAR include: low albumin blood level (hypoalbuminemia), elevated liver enzymes, fever with low white blood cell count, abnormal elevation of triglyceride levels in the blood (hypertriglyceridemia), a high level of blood sugar (hyperglycemia), increased bilirubin level, swelling of the pancreas, abnormal clotting studies, embolic and thrombotic events, allergic reactions, sepsis, and infections.

This is not a complete list of side effects that may occur. Call your doctor for medical advice about any side effects especially if they do not go away.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit

, or call 1-800-FDA-1088. You may also report side effects to Servier Pharmaceuticals LLC at 1-800-807-6124.

For additional information, please refer to the ONCASPAR Full Prescribing Information and discuss any questions with your doctor.

ONCASPAR is a registered trademark of Servier IP UK Ltd., a wholly-owned, indirect subsidiary of Les Laboratoires Servier. Servier and the Servier logo are registered trademarks of Les Laboratoires Servier.